研究業績
論文・著書・解説
2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1996 1994 1993
2018
1. Editorial: Tomizaki, K.-Y.; Hamada, Y.; Usui, K. “Organic-Inorganic Hybrid Materials and Their Applications” Protein & Peptide Letters, 2018, 25 (1), 2-3.
2. Usui, K.; Yokota, S.-I.; Ozaki, M.; Sakashita S.; Imai, T.; Tomizaki, K.-Y. “Modification of the N-Terminus of a Calcium Carbonate Precipitating Peptide Affects Calcium Carbonate Mineralization” Protein & Peptide Letters, 2018, 25(1), 42–47.
3. Tomizaki, K.-Y.; Nanbu, R.; Kasuga, M.; Imai, T. “Incorporation of an N-Methyl Amino Acid into a Template Peptide Alters Anisotropy in the Crystal Growth of Gold Nanoparticles Synthesized by the Peptide Template Method” Protein & Peptide Letters, 2018, 25 (1), 48-55.
4. Tomizaki, K.-Y.; Yamaguchi, Y.; Tsukamoto, N.; Imai, T. “ α-Helical Peptide–Gold Nanoparticle Hybrids: Synthesis, Characterization, and Catalytic Activity” Protein & Peptide Letters, 2018, 25 (1), 56-63.
2017
1. Tomizaki, K.-Y.; Kishioka, K.; Kataoka, S.; Miyatani, M.; Ikeda, T.; Komada, M.; Imai, T.; Usui, K. “Non-Covalent Loading of Anti-Cancer Doxorubicin by Modularizable Peptide Self-Assemblies for a Nanoscale Drug Carrier” Molecules 2017, 22, 1916–1923.
2016
1. Usui, K.; Tomizaki, K.-Y.; Mihara, H. “A Cell Microarray Format: A Peptide Release System Using a Photo-Cleavable Linker for Cell Toxicity and Cell Uptake Analysis” Methods Mol. Biol., 2016, 1352, 97–110.
2. Syahir, A.; Tomizaki, K.-Y.; Kajikawa, K.; Mihara, H. “Anomalous Reflection of Gold: A Novel Platform for Biochips” Methods Mol. Biol., 2016, 1352, 199–210.
Inside Back Cover feature for the issue containing paper (3):
3. Ozaki, M.; Nagai, K.; Nishiyama, H.; Tsuruoka, T.; Fujii, S.; Endoh, T.; Imai, T.; Tomizaki, K.-Y.; Usui, K. “Site-Specific Control of Silica Mineralization on DNA Using a Designed Peptide” Chem. Commun., 2016, 52, 4010–4013.
4. Tomizaki, K.-Y.; Tanaka, A.; Shimada, H.; Nishizawa, K.; Wada, T.; Imai, T. “The Alkyl Linkers in Tandem-Homodimers of a β-Sheet-Forming Nonapeptide Affect the Self-Assembled Nanostructures” Bioorg. Med. Chem. Lett., 2016, 26, 2659–2662.
Inside Back Cover feature for the issue containing paper (5):
5. Usui, K.; Ozaki, M.; Yamada, A.; Hamada, Y.; Tsuruoka, T.; Imai, T.; Tomizaki, K.-Y.“Site-Specific Control of Multiple Mineralizations Using a Designed Peptide and DNA” Nanoscale, 2016, 8, 17081–17084.
2015
1. Syahir, A.; Usui, K.; Tomizaki, K.-Y.; Kajikawa, K.; Mihara, H. “Label and Label-Free Detection Techniques for Protein Microarrays” Microarrays, 2015, 4, 228–244.
2. Tomizaki, K.-Y.; Kishioka, K.; Kobayashi, H.; Kobayashi, A.; Yamada, N.; Kataoka, S.; Imai, T.; Kasuno, M. “Roles of Aromatic Side Chains and Template Effects of the Hydrophobic Cavity of a Self-Assembled Peptide Nanoarchitecture for Anisotropic Growth of Gold Nanocrystals” Bioorg. Med. Chem., 2015, 23, 7282–7291.
2014
1. Tomizaki, K.-Y.; Wakizaka, S.; Yamaguchi, Y.; Kobayashi, A.; Imai, T. “Ultrathin Gold Nanoribbons Synthesized within the Interior Cavity of a Self-Assembled Peptide Nanoarchitecture” Langmuir, 2014, 30, 846–856.
2013
1. Kakiyama, T.; Usui, K.; Tomizaki, K.-Y.; Mie, M.; Kobatake, E.; Mihara, H. “A Peptide Release System Using a Photo-Cleavable Linker in a Cell Array Format for Cell-Toxicity Analysis” Polymer J., 2013, 45, 535–539.
2. Usui, K.; Kikuchi, T.; Tomizaki, K.-Y.; Kakiyama, T.;Mihara, H. “Novel Array Format for Monitoring Cellular Uptake Using a Photo-Cleavable Linker for Peptide Release” Chem. Commun. , 2013, 49, 6394–6396.
2012
“Selected Papers” of the issue (1):
1. Tomizaki, K.-Y.; Obi, M.; Mihara, H. “Noncompetitive On-Chip Immunoassays for Detection of Nonlabeled Antibodies Based on the Excluded Volume Effect of the Target Itself” Bull. Chem. Soc. Jpn. 2012, 85, 69–78.
2. Tomizaki, K.-Y.; Kurosawa, T.; Kajiyama, M.; Imai, T. “Noncovalent Modification of Carbon Nanotubes with Proteins via Biotinylated Peptides Having a Binary Pattern within the Sequences” Chem. Lett. 2012, 41, 597–599.
3. Tomizaki, K.-Y.; Ikawa, T.; Ahn, S.-A.; Yamazoe, S.; Imai, T. “The Effects of Charges at the N- and C-Termini of Short Peptides on Their Secondary and Self-Assembled Structures” Chem. Lett. 2012, 41, 549-551.
4. Taniguchi, I.; Ootera, Y.; Chowdhury, F. A.; Tomizaki, K.-Y.; Kai, T.; Kazama, S. “Polymeric Membranes Composed of Polystyrenes Tethering Amino Acids for Preferential CO2 Separation over H2” Polymer Bulletin, 2012, 69, 405-415.
5. 臼井健二, 富崎欣也, 三原久和「“オミクス”研究に向けた設計アレイの構築」 分析化学 (Bunseki Kagaku), 2012, 61, 523–534.
6. Tomizaki, K.-Y.; Kubo, S.; Ahn, S.-A.; Satake, M.; Imai, T. “Biomimetic Alignment of Zinc Oxide Nanoparticles along a Peptide Nanofiber” Langmuir, 2012, 28, 13459–13466.
7. Tomizaki, K.-Y.; Ahn, S.-A.; Imai, T. “Synthesis of Silica Nanofibers Templated by Self-Assembled Peptide Nanostructures” Trans. Mater. Res. Soc. Jpn., 2012, 37, 541-546.
2011
1. Tomizaki, K.-Y.; Kotera, T.; Naito, H.; Wakizaka, S.; Yamamoto, S.-I. “Design, Synthesis, and Characterization of Self-Assembled Peptide Nanostructures toward Peptide-directed Biomineralization” Chem. Lett. 2011, 40, 699–701.
2. Usui, K.; Kakiyama, T.; Tomizaki, K.-Y.; Mie, M.; Kobatake, E.; Mihara, H. “Cell Fingerprint Patterns using Designed α-Helical Peptides to Screen for Cell-Specific Toxicity” Bioorg. Med. Chem. Lett. 2011, 21, 6281–6284.
2010
1. 富崎欣也、三原久和「酵素利用技術大系—基礎•解析から改変•高機能化•産業利用まで—、第4編 酵素を創るII—化学的改変と人工酵素、第5章 人工酵素、第7節 人工金属酵素—ポルフィリン含有ペプチド」エヌティーエス出版、2010, 390–394.
2. Tomizaki, K.-Y.; Shimizu, S.; Onoda, M.; Fujioka, Y. “Heats of Reaction and Vapor-Liquid Equilibria of Novel Chemical Absorbents for Absorption/Recovery of Pressurized Carbon Dioxide in Integrated Coal Gasification Combined Cycle-Carbon Capture and Storage Process” Ind. Eng. Chem. Res., 2010, 49, 1214–1221.
3. Tomizaki, K.-Y.; Kanakubo, M.; Nanjo, H.; Shimizu, S.; Onoda, M.; Fujioka, Y. “13C NMR Studies on the Dissolution Mechanisms of Carbon Dioxide in Amine-Containing Aqueous Solvents at High Pressures toward an Integrated Coal Gasification Combined Cycle-Carbon Capture and Storage Process” Ind. Eng. Chem. Res., 2010, 49, 1222–1228.
4. Tomizaki, K.-Y.; Usui, K.; Mihara, H. “Protein–Protein Interactions and Selection: Array-Based Techniques for Screening Disease-Associated Biomarkers in Predictive/Early Diagnostics” FEBS J. 2010, 277, 1996–2005.
5. Kirmaier, C.; Song, H.-e.; Yang, E.; Schwartz, J.; Hindin, E.; Diers, J.; Loewe, R.; Tomizaki, K.-Y.; Chevalier, F.; Ramos, L.; Birge, R.; Lindsey, J. S.; Bocian, D. F.; Holten, D. “Excited-State Photodynamics of Perylene–Porphyrin Dyads 5. Tuning Light–Harvesting Characteristics via Perylene Substituents, Connection Motif, and 3-Dimensional Architecture” J. Phys. Chem. B 2010, 114, 14249–14264.
6. Yamamoto, S.-I.; Tomizaki, K.-Y.; Yoshioka, H.; Uraoka, Y.; Yamashita, I.; Hasegawa, S. “Dynamic Evaluation of Processive Movement by Individual Supermolecular Ferritin using High-Speed AFM” Trans. Mater. Res. Soc. Jpn. 2010, 35, 987–992.
2009
1. Tomizaki, K.-Y.; Usui, K.; Mihara, H. “Proteins: Array-Based Techniques” Wiley Encyclopedia of Chemical Biology (Ed. Begley, T. P.), 2009, 144–158.
2. Usui, K.; Tomizaki, K.-Y.; Mihara, H. “A Designed Peptide Chip: Protein Fingerprinting Technology with a Dry Peptide Array and Statistical Data Mining” Methods Mol. Biol. 2009, 570, 273–284.
3. 臼井健二、富崎欣也、 三原久和「超分子サイエンス＆テクノロジー、第4章 バイオ超分子、第5節 ナノバイオデバイス、プロテインチップデバイス」エヌティーエス出版、2009, 1067–1075.
4. Syahir, A; Tomizaki, K.-Y.; Kajikawa, K.; Mihara, H. “Poly(amidoamine)dendrimer-Modified Gold Surfaces for Anomalous Reflection of Gold (AR) Method to Detect Biomolecular Interactions” Langmuir, 2009, 25, 3667–3674.
2008
1. Tomizaki, K.-Y.; Shimizu, S; Onoda, M.; Fujioka, Y. “An Acid Dissociation Constant (pKa)-Based Screening of Chemical Absorbents that Preferably Capture and Release Pressurized Carbon Dioxide for Greenhouse Gas Control” Chem. Lett., 2008, 37, 516–517. 2007
1. Watanabe, S.; Tomizaki, K.-Y.; Takahashi, T.; Usui, K.; Kajikawa, K.; Mihara, H. “Interactions between Peptides Containing Nucleobase Amino Acids (NBAs) and T7 Phages Displaying S. Cerevisiae Proteins” Biopolymers, 2007, 88, 131–140.
2. Usui, K.; Tomizaki, K.-Y.; Mihara,. H. “Screening of α-Helical Peptide Ligands Controlling a Calcineurin-Phosphatase Activity” Bioorg. Med. Chem. Lett. 2007, 17, 167–171.
3. Tomizaki, K.-Y.; Mihara, H. “Phosphate-Mediated Molecular Memory Driven by Two Different Protein Kinases as Information Input Elements” J. Am. Chem. Soc., 2007, 129, 8345–8352.
4. 富崎欣也, 三原久和「タンパク質検出チップ」未来材料、エヌ・ティー・エス、2007年6月号, pp28–38.
5. 富崎欣也, 臼井健二, 三原久和「ペプチドライブラリを用いるタンパク質相互作用検出チップ」Electrochemistry（電気化学および工業物理化学）2007, 75, 981–986.
6. 富崎欣也、三原久和「今日からモノ知りシリーズ、トコトンやさしいタンパク質の本、第7章 プロテインチップでタンパク質を検出」日刊工業新聞社、2007, 122–123.
7. 富崎欣也、三原久和「ナノバイオ計測の実際、第3章 プロテインチップ」講談社サイエンティフィク、2007, 19–30.
8. 富崎欣也、三原久和「新しいDNAチップの科学と応用、第4章–1 プロテインチップの開発」 講談社サイエンティフィク、2007, 171–183.
9. 富崎欣也、三原久和「マイクロアレイ・バイオチップの最新技術、第11章 ペプチドチップ」シーエムシー出版、2007, 240–252.
2006
1. Usui, K.; Tomizaki, K.-Y.; Ohyama, T.; Nokihara, K.; Mihara, H. “A Novel Peptide Microarray for Protein Detection and Analysis Utilizing a Dry Peptide Array System” Mol. BioSyst. 2006, 2, 113–121. Chemical Biology Virtual Journal (RSC Publishing), 2006, Issue 3. Chemical Biology (RSC Publishing) 2006, 3, Additional Web Content.
Cover feature for the issue containing paper (2):
2. Usui, K.; Tomizaki, K.-Y.; Mihara, H. “Protein-Fingerprint Data Mining of a Designed α-Helical Peptide Array” Mol. BioSyst. 2006, 2, 417–420.
Selected as feature article (3):
3. Tomizaki, K.-Y.; Mihara, H. “Rational Design of Homogenous Protein Kinase Assay Platforms that Allow both Fluorometric and Colorimetric Signal Readouts” Mol. BioSyst. 2006, 2, 580–589. Chemical Biology Virtual Journal (RSC Publishing),2006, Issue 5.
Selected as feature article (4):
4. Sano, S.; Tomizaki, K.-Y.; Usui, K.; Mihara, H. “A PNA–DNA Hybridization Chip Approach for the Detection of β-Secretase Activity” Bioorg. Med. Chem. Lett. 2006, 16, 503–506.
5. 富崎欣也、三原久和「一細胞定量解析の最前線~ライフサーベイヤ構築に向けて~、2章–4ペプチドチップテクノロジーによるシグナル解析」シーエムシー出版、2006, 38–51.
2005
1. Usui, K.; Ojima, T.; Tomizaki, K.-Y.; Mihara, H. “A Designed Glycopeptide Array for Characterization of Sugar-Binding Proteins toward a Glycopeptide Chip Technology” NanoBiotechnology 2005, 1, 191–200.
Selected as feature article (2):
2. Watanabe, S.; Usui, K.; Tomizaki, K.-Y.; Kajikawa, K.; Mihara H. “Anomalous Reflection of Gold Applicable for a Practical Protein-Detecting Chip Platform” Mol. BioSyst. 2005, 1, 363–365. Chemical Biology Virtual Journal (RSC Publishing), 2005, Issue 22. Chemical Biology (RSC Publishing) 2006, 1, B1.
Top 10 downloaded ChemBioChem articles for the first six months of 2005 (3):
Cover feature for the issue containing paper (3):
3. Tomizaki, K.-Y.; Usui, K.; Mihara, H. “Protein–Detecting Microarrays: Current Accomplishments and Requirements” ChemBioChem 2005, 6, 782–799. ChemBioChem 2006, 7, 4.
4. Tomizaki, K.-Y.; Xu, Jie; Mihara, H. “A Chromism-Based Assay (CHROBA) Technique for in situ Detection of Protein Kinase Activity” Bioorg. Med. Chem. Lett. 2005, 15, 1731–1735.
5. Tomizaki, K.-Y.; Mihara, H. “A Novel Fluorescence Sensing System Using Photochromism-Based Assay (P-CHROBA) Technique for Detection of Target Proteins” J. Mater. Chem. 2005, 15, 2732–2740.
6. Arai, T.; Ishibashi, K.; Tomizaki, K.-Y.; Kato, T.; Nishino, N. “Slipping of a Histidine Improved the Peroxidase Activity of a De Novo Designed Polypeptide Packing an Iron Porphyrin” Tetrahedron 2005, 61, 4023–4030.
7. 富崎欣也, 三原久和「設計ペプチドを用いた次世代タンパク質検出システム」日本化学会誌、化学と工業、2005年11月号、pp1321–1324.
2004
1. Tomizaki, K.-Y.; Andrey, L. B.; Taniguchi, M.; Lindsey, J. S. “Synthesis of Phenylethyne-Linked Porphyrin Dyads” Tetrahedron 2004, 60, 2011–2023.
2. Hindin, E.; Kirmaier, C.; Diers, J. R.; Tomizaki, K.-Y.; Taniguchi, M.; Lindsey, J. S.; Bocian, D. F.; Holten, D. “Photophysical Properties of Phenylethyne-Linked Porphyrin and Oxochlorin Dyads” J. Phys. Chem. B 2004, 108, 8190–8200.
3. 軒原清史，大山貴史，臼井健二，米山耕一，富崎欣也，三原久和「ペプチドアレイを用いたプロテインチップの実用化を目指した研究」 高分子論文集, 2004, 61, 523–532.
4. 富崎欣也、三原久和「図解バイオ活用技術のすべて、5章–2プロテインチップ」工業調査会、2004, 164–167.
5. 富崎欣也, 三原久和「バイオ計測の新展開-2-」日刊工業新聞, 2004年1月20日版.
2003
1. Tomizaki, K.-Y.; Nishino, H.; Arai, T.; Kato, T.; Nishino, N. “Aniline-Hydroxylation Activity of a Flavin-Linked βαβα-Type Polypeptide Packing an Iron Porphyrin” Chem. Lett. 2003, 6–7.
2. Tomizaki, K.-Y.; Thamyongkit, P.; Loewe, R. S.; Lindsey, J. S. “Practical Synthesis of Perylene-Monoimide Building Blocks that Possess Features Appropriate for Use in Porphyrin-Based Light-Harvesting Arrays” Tetrahedron 2003, 59, 1191–1207.
3. Tomizaki, K.-Y.; Yu, L.; Wei, L.; Bocian, D. F.; Lindsey, J. S. “Synthesis of Cyclic Hexameric Porphyrin Arrays. Anchors for Surface Immobilization and Columnar Self-Assembly” J. Org. Chem. 2003, 68, 8199–8207.
2002
1. Loewe, R. S.; Tomizaki, K.-Y.; Chevalier, F.; Lindsey, J. S. “Synthesis of Perylene–Porphyrin Dyads for Light-Harvesting Studies” J. Porphyrins Phthalocyanines 2002, 6, 626–642.
2. Loewe, R. S.; Tomizaki, K.-Y.; Youngblood, J. W.; Bo, Z.; Lindsey, J. S “Synthesis of Perylene–Porphyrin Building Blocks and Rod-Like Oligomers for Light-Harvesting Applications” J. Mater. Chem. 2002, 12, 3438–3451.
3. Tomizaki, K.-Y.; Loewe, R. S.; Kirmaier, C.; Schwartz, J. K.; Retsek, J. L.; Bocian, D. F.; Holten, D.; Lindsey, J. S. “Synthesis and Photophysical Properties of Light-Harvesting Arrays Comprised of a Porphyrin Bearing Multiple Perylene-Monoimide Accessory Pigments” J. Org. Chem. 2002, 67, 6519–6534. 2001
1. Komatsu, Y.; Tomizaki, K.-Y.; Tsukamoto, M.; Kato, T.; Nishino, N.; Sato, S.; Yamori, T.; Tsuruo, T.; Furumai, R.; Yoshida, M.; Horinouchi, S.; Hayashi, H. “Cyclic Hydroxamic-Acid-Containing Peptide 31, a Potent Synthetic Histone Deacetylase Inhibitor with Antitumor Activity” Cancer Res. 2001, 61(11), 4459–4466. 2000
1. Tomizaki, K.-Y.; Tsunekawa, T.; Akisada, H.; Mihara, H.; Nishino, N. “Design and Characterization of Flavoenzyme Models in the Course of Chemical Evolution of Four-α-Helix Bundle Polypeptides” J. Chem. Soc., Perkin Trans. 2 2000, 813–822.
2. Tomizaki, K.-Y.; Murata, T.; Kaneko, K.; Miike, A.; Nishino, N. “Chiral Assembly of a Pair of Free Base Porphyrins and Peroxidase-Like Activity of Iron(III) Porphyrins in Four-α-Helix Bundle Structures with Dimerized Two-α-Helix Polypeptides" J. Chem. Soc., Perkin Trans. 2 2000, 1067–1074.
3. Tomizaki, K.-Y.; Nishino, H.; Kato, T.; Miike, A.; Nishino, N. “De Novo Design of Hemoprotein Model with Peroxidase Activity toward Lipophilic Peroxide” Chem. Lett. 2000, 648–649.
1996
1. Mihara, H.; Tomizaki, K.-Y.; Fujimoto, T.; Sakamoto, S.; Aoyagi, H.; Nishino, N. “Artificial Membrane Protein Functionalized with Electron Transfer System” Chem. Lett. 1996, 187–188.
2. Kashimoto, K.; Nagano, Y.; Suitani, Y.; Hamanaka, K.; Mizumoto, T.; Tomizaki, K.-Y.; Takahata, H. Nagamoto, A.; Ohata, A.; Yoshihara, S.; Ichimura, T. “Structure–Activity Relationship Studies of PACAP-27 and VIP Analogues” Ann. N.Y. Acad. Sci. 1996, 805, 505–510. 1994
1. Mihara, H.; Tomizaki, K.-Y.; Nishino, N.; Fujimoto, T.; Tamaoki, H.; Kobayashi, Y. “Design, Synthesis, and Conformation of a Model Peptide of Endothelin with Cystine-Stabilized α-Helix Motif” Biopolymers 1994, 34, 963–967.
1993
1. Mihara, H.; Tomizaki, K.-Y.; Nishino, N.; Fujimoto, T. “De Novo Design and Synthesis of Four-α-Helix Bundle Proteins with Flavin Function” Chem. Lett. 1993, 1533–1536.
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